We describe two new species of lowland Litoria from Normanby Island, off the southeastern tip of New Guinea. One new species is a medium-sized member of the Litoria thesaurensis species group and differs from the other three members of that group in having a combination of white bones, extensive webbing, a loud quacking call, and a uniformly yellow color pattern. The second species is apparently a member of the Litoria bicolor species group and differs from other Papuan members of that group in a number of important morphological features (relative head shape, absence of vomerine teeth, absence of alary processes on the hyoid) that suggest the L. bicolor species group may not be a monophyletic assemblage. Both new species are currently known with certainty only from Normanby Island but seem likely to occupy at least the remainder of the D'Entrecasteaux archipelago as well.