Larval records, distributional records, biological information, and comments on probable erroneous literature records are presented for 55 species and subspecies of North American Cerambycidae in the genera Mallodon Lacordaire, Orthosoma Audinet-Serville, Aethecerinus Fall and Cockerell, Aneflomorpha Casey, Anelaphus Linsley, Calloides LeConte, Cyrtophorus LeConte, Eburia Lacordaire, Elaphidionopsis Linsley, Elytroleptus Dugés, Enaphalodes Haldeman, Euderces LeConte, Heterachthes Newman, Lissonotus Dalman, Megacyllene Casey, Microclytus LeConte, Neaneflus Linsley, Neoclytus Thomson, Obrium Dejean, Pentanodes Schaeffer, Phymatodes Mulsant, Piezocera Audinet-Serville, Pilostenaspis Eya, Psyrassa Pascoe, Purpuricenus Dejean, Rosalia Audinet-Serville, Semanotus Mulsant, Stenaspis Audinet-Serville, Tessaropa Haldeman, Tilloclytus Bates, Tragidion Audinet-Serville, Xylotrechus Chevrolat, Necydalis Linnaeus, Neobellamira Swaine and Hopping, Strangalia Audinet-Serville, Typocerus LeConte, Ataxia Haldeman, Cacostola Fairmaire and Germain, Goes LeConte, Oberea Mulsant, Oncideres Lacordaire, Phaea Newman, and Saperda Fabricius. First larval host records are presented for 11 species: Aneflomorpha luteicornis Linsley, Aneflomorpha parkeri Knull, Elytroleptus ignitus (LeConte), Elytroleptus immaculipennis Knull, Pentanodes dietzi Schaeffer, Phymatodes lengi Joutel, Psyrassa castanea Bates, Purpuricenus opacus (Knull), Stenaspis verticalis arizonicus Casey, Typocerus gloriosus Hopping, and Cacostola lineata Hamilton.