Seven new species and one new variety of Hypolepis are presented, bringing the total recognized for the genus in the Neotropics to about 50 species (and a total of 60 taxa). The new taxa include H. barringtonii (endemic to Florida, U.S.A.), H. cubensis (endemic to Cuba), H. feeana (from Colombia, Venezuela, and the Antilles), H. zimmerae (from Costa Rica, Colombia, Ecuador, and Peru), H. sunduei (endemic to Peru), H. forzzae (endemic to Amazonas, in the border of Brazil and Venezuela), H. miodelii (endemic to Rio de Janeiro, Brazil), and H. rigescens var. paranaensis (endemic to Paraná, Brazil). All new taxa are described, illustrated, and discussed. Treatments of H. flexuosa and H. stuebelii are provided because the description of H. zimmerae and H. feeana alters their circumscription, respectively. It is also suggested that H. repens does not occur in Florida, Cuba, nor Jamaica.