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1 October 2002 Pathogenicity of Embryo-Adapted Serotype 2 OH Strain of Infectious Bursal Disease Virus in Chickens and Turkeys
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Abstract

The pathogenicity of serotype 2 OH strain of infectious bursal disease virus (IBDV) to specific-pathogen-free (SPF) chicken embryos and 2-wk-old SPF chickens and turkey poults was investigated. The virus was pathogenic for chicken embryos after five passages as evidenced by pathologic changes in inoculated embryos. The embryo-adapted virus was not pathogenic for 2-wk-old SPF chickens and turkey poults as indicated by lack of clinical signs, gross or microscopic lesions in the bursa of Fabricius of inoculated birds. Bursa-to-body-weight ratios of the inoculated chickens and turkey poults were not significantly different from those of uninoculated controls. Virus-neutralizing antibodies to serotype 2 IBDV were detected in inoculated chickens and turkeys. Results of this study indicated that the embryo-adapted serotype 2 OH IBDV isolate that is pathogenic for chicken embryos is infectious but not pathogenic in chickens and turkeys.

G. A. Abdel-Alim and Y. M. Saif "Pathogenicity of Embryo-Adapted Serotype 2 OH Strain of Infectious Bursal Disease Virus in Chickens and Turkeys," Avian Diseases 46(4), 1001-1006, (1 October 2002). https://doi.org/10.1637/0005-2086(2002)046[1001:POEASO]2.0.CO;2
Received: 2 January 2002; Published: 1 October 2002
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