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1 March 2008 The Effects of Increasing Sodium Chloride Concentration on Mycoplasma gallisepticum Vaccine Survival in Solution
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Abstract

Lyophilized Mycoplasma gallisepticum (MG) vaccines are generally rehydrated and diluted with distilled or chlorine-free water as per manufacturer recommendations. However, as mycoplasma species lack a cell wall, this can lead to decreased viability of live vaccine during administration. The ability of phosphate-buffered saline (PBS) to prevent losses in live vaccine viability was examined. It was shown that a concentration of 1× PBS prevented the two–fourfold decrease in MG viability seen when the vaccines were diluted with water alone.

S. A. Leigh, J. D. Evans, S. L. Branton, and S. D. Collier "The Effects of Increasing Sodium Chloride Concentration on Mycoplasma gallisepticum Vaccine Survival in Solution," Avian Diseases 52(1), 136-138, (1 March 2008). https://doi.org/10.1637/7979-040507-ResNote
Received: 5 April 2007; Accepted: 1 August 2007; Published: 1 March 2008
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