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1 May 2006 Mechanism of Action of l-arginine on the Vitality of Spermatozoa is Primarily Through Increased Biosynthesis of Nitric Oxide
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Abstract

The ability of sperm to fertilize the egg is primarily dependent on sperm motility and membrane integrity. Nitric oxide (NO) plays a decisive role in regulating multiple functions within the male reproductive system. The aim of the present study is to determine the mechanism by which l-arginine confers a protective action on spermatozoa obtained from the goat epididymis. NO is synthesized from l-arginine by the enzyme nitric oxide-synthase (NOS) present in spermatozoa. A possible participation of NO and NOS in arginine action has been suggested.

Sudha Srivastava, Prashant Desai, Evans Coutinho, and Girjesh Govil "Mechanism of Action of l-arginine on the Vitality of Spermatozoa is Primarily Through Increased Biosynthesis of Nitric Oxide," Biology of Reproduction 74(5), 954-958, (1 May 2006). https://doi.org/10.1095/biolreprod.105.046896
Received: 25 August 2005; Accepted: 1 January 2006; Published: 1 May 2006
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