Translator Disclaimer
1 June 2007 Beat shock proteins and atrial fibrillation
Author Affiliations +
Abstract

In this mini-review, the role of heat shock proteins in susceptability to induction of atrial fibrillation (AF) or in the process of AF is discussed. AF is the most common arrhythmia in humans, is self-perpetuating in nature and hence tends to become more persistent in time. Some studies show a correlation between high Hsp70 (HspA1A) expression in cardiac tissue and a reduced susceptability to induction of postoperative AF. Expression of Hsp70, Hsc70 (HspA8), Hsp40 (DnaJB1), Hsp60 (HspD1), Hsp90 (HspC1) was not associated with progression of AF. However, both correlative studies in human and experimental studies suggest that Hsp27 (HspB1) may delay progression of AF to the more permanent forms and hence Hsp27 might be referred to as a “Beat shock protein”.

Harm H. Kampinga, Robert H. Henning, Isabelle C. van Gelder, and Bianca J. J M. Brundel "Beat shock proteins and atrial fibrillation," Cell Stress & Chaperones 12(2), (1 June 2007). https://doi.org/10.1379/CSC-285.1
Received: 11 April 2007; Accepted: 1 April 2007; Published: 1 June 2007
JOURNAL ARTICLE
4 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top