Translator Disclaimer
1 October 2003 LIFE HISTORY AND THE MALE MUTATION BIAS
Author Affiliations +
Abstract

If DNA replication is a major cause of mutation, then those life-history characters, which are expected to affect the number of male germline cell divisions, should also affect the male to female mutation bias (αm). We tested this hypothesis by comparing several clades of bird species, which show variation both in suitable life-history characters (generation time as measured by age at first breeding and sexual selection as measured by frequency of extrapair paternity) and in αm, which was estimated by comparing Z-linked and W-linked substitution rates in gametologous introns. αm differences between clades were found to positively covary with both generation time and sexual selection, as expected if DNA replication causes mutation. The effects of extrapair paternity frequency on αm suggests that increased levels of sexual selection cause higher mutation rates, which offers an interesting solution to the paradox of the loss of genetic variance associated with strong directional sexual selection. We also used relative rate tests to examine whether the observed differences in αm between clades were due to differences in W-linked or Z-linked substitution rates. In one case, a significant difference in αm between two clades was shown to be due to W-linked rates and not Z-linked rates, a result that suggests that mutation rates are not determined by replication alone.

Anna Bartosch-Härlid, Sofia Berlin, Nick G. C. Smith, Anders P. Møller, and Hans Ellegren "LIFE HISTORY AND THE MALE MUTATION BIAS," Evolution 57(10), 2398-2406, (1 October 2003). https://doi.org/10.1554/03-036
Received: 15 January 2003; Accepted: 1 March 2003; Published: 1 October 2003
JOURNAL ARTICLE
9 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top