Insect pests, including caterpillars, cause losses in maize (Zea mays L.; Poaceae) which is one of the most important agricultural crops in the world. The objective of this study was to evaluate the management of Spodoptera frugiperda Smith & Abbot (Lepidoptera: Noctuidae) with transgenic and conventional maize genotypes. The experiments were conducted in the field in summer crops from the seasons 2014/2015 and 2015/2016 in a randomized complete block design with sub-subdivided plots represented by: control (no control), chemical control (methomyl + diflubenzurom), Integrated Pest Management–spinosade, and biological control (Trichogramma pretiosum Riley; Hymenoptera: Trichogrammatidae) with 3 maize genotypes (Impact VIP 3, P3862 HX, and BM 3061) and 4 replications. Control and reduction of S. frugiperda damage were higher in the Impact VIP 3 corn genotype. The crop yield was higher (11,838.59 kg per h^-1), and the damage to the ears was lower in the biological control with T. pretiosum.