Empoasca terminalis Distant (Hemiptera: Cicadellidae) is a new and increasingly important pest of soybean in South Sulawesi Province of Indonesia. Soybean producers rely heavily on insecticide use to control the insect; hence there is an urgency of finding alternative control measures that are effective and safer. The use of resistant cultivars well meet these criteria. Field studies were initiated to evaluate the susceptibility of several commercial soybean varieties against the leafhopper. Twelve soybean cultivars: ‘Gepak Kuning’, ‘Kaba’, ‘Mahameru’, ‘Gema’, ‘Detam-2’, ‘Grobogan’, ‘Gepak Ijo’, ‘Willis’, ‘Tidar’, ‘Detam-1’, ‘Argomulyo’, and ‘Anjasmoro’ were evaluated against E. terminalis in 2012 and 2013. The amounts of yield loss due to the leafhopper was also determined in 2012 and 2013. The lowest numbers of adults and nymphs were found on ‘Gepak Kuning’; while the highest numbers of adults and nymphs were found on ‘Mahameru’. Similarly, the lowest and highest scores of hopperburn were also found on these 2 cultivars, respectively. ‘Tidar’, ‘Gepak Ijo’, and ‘Kaba’ were also resistant to the leafhopper. Leafhopper infestation significantly reduced the yields on susceptible cultivars but not on the resistant ones. Our results also showed that trichome density was not associated with the level of resistance of the cultivars to the leafhopper. Our results suggested that ‘Gepak Kuning’, ‘Gepak Ijo’, ‘Tidar’, and ‘Kaba’ are resistant to E. terminalis and should be used by soybean producers to suppress the pest population.