A new species of Gerrhonotus, previously confused with G. infernalis, is described from the Cuatro Ciénegas Basin, Coahuila, Mexico. The new species is known from the type locality only and is characterized by the following combination of characters: a cantholoreal scale usually present, a dark mark extending anteriorly from the lower temporal scales through the lower border of the orbit to the preocular or cantholoreal scales, keeled dorsal scales, dorsal body pattern usually composed of cross-bands mostly interrupted or barely discernible on middorsum, usually indiscernible vertical dark bars on the lateral fold (few, faint bars occasionally present), and black flecks scattered on the venter. The new species is geographically closest to G. lugoi and G. infernalis but morphologically most similar to G. infernalis.