HLA Class I Antigen and HLA-A, -B, and -C Haplotype Frequencies in Uruguayans

Ines Alvarez; Milka Bengochea; Roberto Toledo; Elena Carretto; Pedro C. Hidalgo

doi:10.1353/hub.2006.0051

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Ines Alvarez,^* Milka Bengochea,^* Roberto Toledo,^* Elena Carretto,^* Pedro C. Hidalgo^*

^*Laboratorio de Inmunogenética e Histocompatibilidad, Instituto Nacional de Trasplante y Donación de Células, Tejidos y Órganos (INDT), Hospital de Clínicas “Manuel Quintela,” Ave. Italia s/n Piso 4, CP 11600, Montevideo, Uruguay.

Abstract

HLA class I antigens were determined for 959 unrelated Uruguayans. The predominant HLA alleles were A2, Cw4, and B35, and the most frequently observed two-loci haplotypes were A2-B44 and B35-Cw4. The most frequent three-loci HLA haplotype was A2-Cw5-B44. We compared the Uruguayan sample with similar data from other populations.

Citation Download Citation

Ines Alvarez, Milka Bengochea, Roberto Toledo, Elena Carretto, and Pedro C. Hidalgo "HLA Class I Antigen and HLA-A, -B, and -C Haplotype Frequencies in Uruguayans," Human Biology 78(4), 513-525, (1 August 2006). https://doi.org/10.1353/hub.2006.0051

Received: 2 May 2005; Published: 1 August 2006

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