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The marine breeding and healthy aquaculture industry in Shandong Peninsula should seek breakthroughs in three aspects: the transformation of production mode, the combination of production, education and research technological innovation. The marine high-end equipment manufacturing industry should focus on the industrial chain restructuring and industrial clusters. With the innovation of industrial organization mode as the main body, we seek to improve the ability of independent innovation through various forms of technological innovation activities.The development of the marine bio-pharmaceutical industry should do a good job in integrating and upgrading the biotechnology industrial park and creating an industrial technology innovation alliance.