The invasive kudzu bug, Megacopta cribraria (F.) (Hemiptera: Plataspidae), has become an economic pest of soybean, Glycine max (L.) Merrill, in the southeastern United States since its initial discovery in Georgia. Information on management practices, including insecticides, is limited due to its uncertain pest status in its native range and recent introduction to the United States. We evaluated the efficacy in controlling M. cribraria and economic benefits of a variety of insecticides labeled for use in soybean from different chemical classes in field trials in South Carolina and Georgia from 2010 through 2012. Several pyrethroids were among the most effective insecticides for control of M. cribraria. The pyrethroid bifenthrin had an immediate (2–6 d after treatment application) percentage of control of 97.5 ± 0.2% (SEM), which was the highest of the active ingredients tested. Likewise, net marginal benefits were typically greatest for pyrethroids, either alone or tank-mixed with other materials. Our results confirm that chemical control of M. cribraria in commercial soybean production is economically viable, but the number of effective chemical classes is limited.