Leptophis santamartensis, known only from Sierra Nevada de Santa Marta, Colombia, is one of the more poorly known species of the genus Leptophis. The characters used for its diagnosis largely overlap with those of other Leptophis, mainly with Leptophis ahaetulla occidentalis, the only other Leptophis known to occur in the Sierra Nevada de Santa Marta. A detailed comparison of L. a. occidentalis with the two known specimens of L. santamartensis leads to the conclusion that the latter should be relegated to the synonymy of the former.