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1 October 2017 Inflammatory Mediators in Ovarian Follicles: The Possible Role of Platelet-Activating Factor and its Metabolic Enzyme
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Abstract

Platelet-activating factor (PAF) is a potent proinflammatory negotiator that shows a distinct spectrum of biological and pharmacological effects and participates in a wide range of pathophysiological conditions. In the reproductive system, PAF has been shown to have an important role in initiating ovulation, progesterone production and chemokine production. The purpose of this article was to review the roles of PAF, a well-known family of messenger phospholipids, in the reproductive process, especially in ovulation. This review highlights the interesting parallels between PAF's mechanism in ovulation and inflammatory process.

©2017 Japan Society for Ova Research
Yasushi Kawano, Emi Harada, Yuki Yamashita, Yui Itonaga, Naomi Inoue, and Hisashi Narahara "Inflammatory Mediators in Ovarian Follicles: The Possible Role of Platelet-Activating Factor and its Metabolic Enzyme," Journal of Mammalian Ova Research 34(2), (1 October 2017). https://doi.org/10.1274/jmor.34.47
Received: 30 May 2017; Accepted: 1 July 2017; Published: 1 October 2017
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