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1 January 2000 Optically Active Arthropod Repellents for Use Against Disease Vectors
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Abstract

Optically inactive 1-[3-cyclohexen-1-ylcarbonyl] piperidine and 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine are repellents against blood-feeding arthropods. Pure stereoisomers of these compounds were synthesized and characterized for use in bioassays. Initial laboratory tests with the malaria vector Anopheles stephensi Liston showed that this species was repelled differentially by the stereoisomers of 1-[3-cyclohexen-1-ylcarbonyl]-2-methylpiperidine. Two stereoisomers were twice as repellent as the other stereoisomers. These results indicate that stereoisomerism influences repellent efficacy in this class of compounds.

Jerome A. Klun, Da Ma, and Raj Gupta "Optically Active Arthropod Repellents for Use Against Disease Vectors," Journal of Medical Entomology 37(1), 182-186, (1 January 2000). https://doi.org/10.1603/0022-2585-37.1.182
Received: 4 May 1999; Accepted: 1 September 1999; Published: 1 January 2000
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