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1 October 2001 Cutaneous Leishmaniasis Infection in Balb/c Mice Using a Leishmania tropica Strain Isolated From Turkey
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Abstract

Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 × 107) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously into the footpads of 10 Balb/c mice. Cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. Leishmania tropica amastigotes were observed in smear slides and then cultivated in NNN medium. Balb/c mice are a suitable laboratory model for this isolate of L. tropica and thus a source of amastigotes for studies on the immunology, chemotherapy, and pathogenicity of cutaneous leishmaniasis.

Nogay Girginkardeşler, İCüneyt Balcıoğlu, Kor Yereli, Ahmet Özbilgin, and Yusuf Özbel "Cutaneous Leishmaniasis Infection in Balb/c Mice Using a Leishmania tropica Strain Isolated From Turkey," Journal of Parasitology 87(5), (1 October 2001). https://doi.org/10.1645/0022-3395(2001)087[1177:CLIIBC]2.0.CO;2
Published: 1 October 2001
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