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1 April 2009 Transmission of Different Strains of Plasmodium cynomolgi to Aotus nancymaae Monkeys and Relapse
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Abstract
Forty-four splenectomized Aotus nancymaae monkeys were infected with 6 different strains of Plasmodium cynomolgi, 11 via trophozoites and 33 via sporozoites. Sporozoites from Anopheles dirus, Anopheles freeborni, Anopheles gambiae, Anopheles maculatus, and Anopheles stephensi resulted in prepatent periods ranging from 9 to 39 days (median of 15 days). Importantly, relapse was demonstrated in 5 of 5 sporozoite-induced infections with the Rossan strain following treatment with chloroquine.
William E. Collins, Jo Ann S. Sullivan, Douglas Nace, Tyrone Williams, Allison Williams and John W. Barnwell "Transmission of Different Strains of Plasmodium cynomolgi to Aotus nancymaae Monkeys and Relapse," Journal of Parasitology 95(2), (1 April 2009). https://doi.org/10.1645/GE-1797.1
Received: 23 July 2008; Accepted: 1 September 2008; Published: 1 April 2009
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