Translator Disclaimer
1 August 2011 Inference of Population Structure and Patterns of Gene Flow in Canine Heartworm (Dirofilaria immitis)
Author Affiliations +
Abstract
Understanding the genetic variation within a parasitic species is crucial to implementing successful control programs and preventing the dispersal of drug resistance alleles. We examined the population genetics and structure of canine heartworm (Dirofilaria immitis) by developing a panel of 11 polymorphic microsatellite loci for this abundant parasite. In total, 192 individual nematodes were opportunistically sampled from 9 geographic regions in the United States and Mexico and genotyped. Population genetic analyses indicate the presence of 4 genetic clusters. The canine heartworm samples used in this study were characterized by low heterozygosity, with eastern and central North America experiencing high levels of reciprocal gene flow. Geographic barriers impede the movement of vectors and infected hosts west of the Rocky Mountains and south of the Central Mexican Plateau. This, combined with corridors of contiguous habitat, could influence the spread of drug resistance alleles.
American Society of Parasitologists
Diana H. Belanger, Susan L. Perkins and Robert F. Rockwell "Inference of Population Structure and Patterns of Gene Flow in Canine Heartworm (Dirofilaria immitis)," Journal of Parasitology 97(4), (1 August 2011). https://doi.org/10.1645/GE-2679.1
Received: 14 October 2010; Accepted: 1 February 2011; Published: 1 August 2011
JOURNAL ARTICLE
8 PAGES


SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top