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1 August 2013 E-ADA Activity in Serum of Lambs Experimentally Infected with Haemonchus contortus
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Abstract

The aim of this study was to evaluate adenosine deaminase (E-ADA) activity in sera of lambs experimentally infected with Haemonchus contortus. We used 12 lambs divided into 2 groups; Group A had 5 healthy, non-infected animals (control) and Group B had 7 healthy animals infected with H. contortus. Lambs were infected orally with 500 larvae (L3) per animal every 2 days, for a period of 20 days, and later the infection was confirmed by examination of feces (eggs per gram [EPG] via fecal egg count). Blood collection was performed at days 0, 20, 40, 60, and 80 post-infection (PI) for analysis of E-ADA activity. Animals in Group A showed negative EPG throughout the experiment unlike those from Group B that had elevated EPG counts. E-ADA activity was reduced in the serum of animals infected with H. contortus when compared to non-infected controls at days 20, 40, 60, and 80 PI. Therefore, it is concluded that infection with H. contortus influences the E-ADA activity in lambs.

Aleksandro S. Da Silva, Guilherme C. Fausto, Thirssa H. Grando, Carlos A. Cadore, Victor C. Pimentel, Jeandre A. Jaques, Maria R. C. Schetinger, Silvia G. Monteiro, and Marta L. R. Leal "E-ADA Activity in Serum of Lambs Experimentally Infected with Haemonchus contortus," Journal of Parasitology 99(4), 703-705, (1 August 2013). https://doi.org/10.1645/12-67.1
Published: 1 August 2013
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