Hemorrhagic disease (HD) caused by bluetongue and epizootic hemorrhagic disease viruses occurred in white-tailed deer (Odocoileus virginianus) of seven southeastern states during the late summer and early fall, 1971. The disease first appeared in South Carolina and then erupted almost simultaneously in Florida, Georgia, Kentucky, North Carolina, Tennessee, and Virginia. Peracute, acute, and chronic forms of HD were distinguished. Few gross lesions were observed in peracute HD but hemorrhage and edema commonly were seen in acute HD. Stomatitis and laminitis characterized the chronic disease. Mortality rate appeared to be related to the number of deer on the area.