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1 April 1988 Response of Vaccinated and Unvaccinated Bighorn Sheep (Ovis canadensis canadensis) to Experimental Respiratory Syncytial Virus Challenge
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Abstract

Five Rocky Mountain bighorn sheep (Ovis canadensis canadensis), approximately 5 mo old and without detectable antibody titers to respiratory syncytial virus (RSV), were assigned to two groups to study the effects of RSV challenge inoculation in vaccinated (n = 3) and unvaccinated (n = 2) bighorns. The three lambs vaccinated with a modified live bovine RSV vaccine developed a detectable antibody response to the vaccine. Vaccinated and unvaccinated lambs challenged with an ovine isolate of RSV developed increased levels of neutralizing antibody, but clinical signs of disease were not observed. Neutralizing antibody titers to RSV remained higher (2–4-fold) in vaccinated lambs over time when compared to unvaccinated lambs.

Foreyt and Evermann: Response of Vaccinated and Unvaccinated Bighorn Sheep (Ovis canadensis canadensis) to Experimental Respiratory Syncytial Virus Challenge
William J. Foreyt and James F. Evermann "Response of Vaccinated and Unvaccinated Bighorn Sheep (Ovis canadensis canadensis) to Experimental Respiratory Syncytial Virus Challenge," Journal of Wildlife Diseases 24(2), 356-359, (1 April 1988). https://doi.org/10.7589/0090-3558-24.2.356
Received: 11 September 1987; Published: 1 April 1988
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