Aeromonas hydrophila was isolated from the internal organs of a captive caracal lynx (Felis caracal) which died of acute septicemia. Grossly, patchy areas of focal necrosis were found in the lungs, liver and kidney; there was ulceraction in the stomach and intestines. Microscopically, lesions contained cellular debris, neutrophils, lymphocytes and gram-negative bacilli. This is the first report of isolation of Aeromonas hydrophila from a captive wild animal in Nigeria.