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1 April 1996 Antagonism of Xylazine in White-Tailed Deer with Intramuscular Injection of Yohimbine
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Eighteen free-ranging white-tailed deer (Odocoileus virginianus) were captured near Chestertown, Maryland (USA) from 15 February to 21 March, and 7 October to 13 November 1986. Deer were immobilized by intramuscular injection of 1.1 to 2.2 mg/kg xylazine hydrochloride and 1.8 to 4.4 mg/kg ketamine hydrochloride. Four captive deer from The Pennsylvania State University, Pennsylvania (USA), were immobilized on 16 September 1986 with 1.5 to 2.0 mg/kg xylazine hydrochloride. Intramuscular injection of yohimbine hydrochloride (0.4 mg/kg) was used to antagonize the immobilizations. Free-ranging adult (≥17 months) males could stand after a mean (±SE) time of 7.3 ± 2.4 min, adult females after 8.6 ±1.7 min, male fawns after 5.7 ± 3.3 min, and female fawns after 8.9 ±1.9 min. Captive adult males could stand after 20.2 ± 3.4 min. Intramuscular injections of yohimbine hydrochloride effectively and safely antagonized the xylazine hydrochloride in immobilized deer and were easier to administer than intravenous injections.

Bret D. Wallingford, Richard A. Lancia, and Edward C. Soutiere "Antagonism of Xylazine in White-Tailed Deer with Intramuscular Injection of Yohimbine," Journal of Wildlife Diseases 32(2), 399-402, (1 April 1996).
Received: 1 March 1995; Published: 1 April 1996

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