Infectious Canine Hepatitis in a Brown Bear (Ursus arctos horribilis) from Alaska, USA

Susan Knowles; Barbara L. Bodenstein; Troy Hamon; Michael W. Saxton; Jeffrey S. Hall

doi:10.7589/2017-10-245

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Susan Knowles,^1,* Barbara L. Bodenstein,¹ Troy Hamon,² Michael W. Saxton,^2,3 Jeffrey S. Hall¹

¹1US Geological Survey, National Wildlife Health Center, 6006 Schroeder Road, Madison, Wisconsin 5371
²2Katmai National Park and Preserve, PO Box 7, King Salmon, Alaska 99613, USA
³3School of Biological Sciences, Washington State University, PO Box 644236, Pullman, Washington 9916

^*Corresponding author (email: sknowles@usgs.gov)

Abstract

We diagnosed infectious canine hepatitis in a free-ranging brown bear (Ursus arctos horribilis) cub from Alaska, US, found dead in October 2015. Intranuclear inclusion bodies were present in hepatocytes, and immunohistochemistry showed reactivity to adenoviral antigens. Sequencing of the hexon protein of adenovirus showed 100% identity to canine adenovirus 1.

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Susan Knowles, Barbara L. Bodenstein, Troy Hamon, Michael W. Saxton, and Jeffrey S. Hall "Infectious Canine Hepatitis in a Brown Bear (Ursus arctos horribilis) from Alaska, USA," Journal of Wildlife Diseases 54(3), 642-645, (2 March 2018). https://doi.org/10.7589/2017-10-245

Received: 4 October 2017; Accepted: 11 December 2017; Published: 2 March 2018

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