To better understand distribution and density of fishers (Martes pennanti) in industrial forests of north-central British Columbia, Canada, we examined factors affecting the probability of a potential home range being occupied by 10 radiotagged resident fishers in the Sub-Boreal Spruce biogeoclimatic zone between 1996 and 2000. Percentage of a home range in wetlands and recently logged (within past 12 yr) best predicted likelihood of occupancy by each fisher. Probability of a home range area being occupied by a resident fisher decreased with increasing amounts of wetlands and recent logging present in the area. We estimated that a 5% increase in wetlands or recent logging decreased the relative probability of occupancy of a potential home range by 50%. The accelerated rate of timber harvest in forests affected by mountain pine beetle (Dendroctonus ponderosae) infestations may have substantial implications for the ability of the landscape of central British Columbia to support sustainable populations of fishers.