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1 December 2002 THYROID C-CELL CARCINOMA IN AN AFRICAN PYGMY HEDGEHOG (ATELERIX ALBIVENTRIS)
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Abstract
A 3-yr-old African pygmy hedgehog (Atelerix albiventris) was submitted with dysphagia, weight loss, and tetraparesis. A palpable mass was found on the ventral neck. Histologic examination revealed replacement of the thyroid gland by a highly cellular, expansile, and infiltrative mass composed of lobules of polygonal cells separated by fine fibrovascular septa. Examination of ultrathin sections revealed tumor cells with few to many dense-core neuroendocrine granules, approximately 100–200 nm in diameter, and stromal amyloid. Immunohistochemical stains were positive for neuron-specific enolase. Only rare cells had positive immunohistochemical staining for calcitonin. Findings are consistent with a neuroendocrine tumor of C-cell origin. This is the first report of a C-cell carcinoma in a hedgehog.
Debra L. Miller, Eloise L. Styer, Janeen K. Stobaeus and Terry M. Norton "THYROID C-CELL CARCINOMA IN AN AFRICAN PYGMY HEDGEHOG (ATELERIX ALBIVENTRIS)," Journal of Zoo and Wildlife Medicine 33(4), (1 December 2002). https://doi.org/10.1638/1042-7260(2002)033[0392:TCCCIA]2.0.CO;2
Received: 9 May 2002; Accepted: ; Published: 1 December 2002
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