Between 1991 and 2001 a total of 12 cases of Mycobacterium tuberculosis infection in eight different species were recorded in the National Zoological Gardens of South Africa in Pretoria (Tshwane). The genetic relatedness between seven of the M. tuberculosis isolates was determined by IS6110 restriction fragment length polymorphism analysis. For the majority of isolates that were analyzed, a high degree of polymorphism suggested different sources of infection. Evidence of M. tuberculosis transmission between animals is reported in two chimpanzees (Pan troglodytes) housed together, from which samples were collected for analysis 29 mo apart.
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1 December 2003
MYCOBACTERIUM TUBERCULOSIS INFECTIONS IN EIGHT SPECIES AT THE NATIONAL ZOOLOGICAL GARDENS OF SOUTH AFRICA, 1991–2001
Anita L. Michel,
Leon Venter,
Ian W. Espie,
Morné L. Coetzee
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Journal of Zoo and Wildlife Medicine
Vol. 34 • No. 4
December 2003
Vol. 34 • No. 4
December 2003
anthropozoonosis
IS6110 RFLP typing
Mycobacterium tuberculosis
PCR
TUBERCULOSIS
zoo