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1 June 2012 HEMORRHAGIC ENTEROCOLITIS AND DEATH IN TWO FELINES (PANTHERA TIGRIS ALTAICA AND PANTHERA LEO) ASSOCIATED WITH CLOSTRIDIUM PERFRINGENS TYPE A
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Abstract

Severe hemorrhagic enterocolitis was observed in a Siberian tiger (Panthera tigris altaica) and a lion (Panthera leo). Both animals developed acute depression, anorexia, and bloody diarrhea several days before death. Small and large intestines were diffusely congested, edematous, necrotic, and filled with hemorrhagic fluid, and mesenteric lymph nodes were enlarged and congested. Pure and abundant growth of gram-positive bacilli was obtained in culture under anaerobic conditions from the livers of both felines. Identification of highly virulent Clostridium perfringens Type A was based on pathologic lesions, hemolytic patterns, morphologic structure, and polymerase chain reaction. Animal inoculation assays indicated that C. perfringens Type A played an important role in the pathogenesis of both felines.

American Association of Zoo Veterinarians
Yanlong Zhang, Zhijun Hou, and Jianzhang Ma "HEMORRHAGIC ENTEROCOLITIS AND DEATH IN TWO FELINES (PANTHERA TIGRIS ALTAICA AND PANTHERA LEO) ASSOCIATED WITH CLOSTRIDIUM PERFRINGENS TYPE A," Journal of Zoo and Wildlife Medicine 43(2), 394-396, (1 June 2012). https://doi.org/10.1638/2010-0197.1
Received: 11 January 2011; Published: 1 June 2012
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