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20 September 2012 CEFOVECIN (CONVENIA) FOR THE TREATMENT OF SEPTIC PERITONITIS IN A FEMALE LION (PANTHERA LEO)
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Abstract

An 8-yr-old intact female African lion (Panthera leo) presented with a 3-day history of lethargy, anorexia, and vomiting. Hematologic and biochemical abnormalities included a leukocytosis, 41,700/μl (4,700–15,300) with a neutrophilia (37,530/μl; 2,000–9,200) and a left shift (1,250/μl bands; 0–300), and mild hypokalemia of 2.1 mEq/L (2.8–4.8). Abdominal radiographs revealed evidence of intestinal ileus, peritonitis, and the presence of effusion. An exploratory laparotomy was performed, and septic peritonitis due to a pyometra was diagnosed. The lion was treated with an ovariohysterectomy, abdominal lavage, fluid therapy, and a subcutaneous injection of cefovecin. The lion recovered, and clinical signs associated with septic peritonitis resolved within 36 hr. It was returned to conspecifics 3 wk later. Three months postoperatively, the lion showed no residual signs of septic peritonitis.

American Association of Zoo Veterinarians
James Steeil, Juergen Schumacher, Rachel Seibert, and Karen Tobias "CEFOVECIN (CONVENIA) FOR THE TREATMENT OF SEPTIC PERITONITIS IN A FEMALE LION (PANTHERA LEO)," Journal of Zoo and Wildlife Medicine 43(3), (20 September 2012). https://doi.org/10.1638/2012-0038R.1
Received: 8 February 2012; Published: 20 September 2012
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