Translator Disclaimer
1 June 2013 CHOLANGIOCARCINOMA OF INTRAHEPATIC BILE DUCTS WITH DISSEMINATED METASTASES IN AN AFRICAN LION (PANTHERA LEO)
Author Affiliations +
Abstract

A cholangiocarcinoma is reported in an 18-yr-old, female African lion (Panthera leo). The primary tumor consisted of multifocal to coalescing, hepatic, white–yellow masses distributed throughout the liver lobes. Metastases were present in regional lymph nodes, peritoneal surface, and lungs. Histologically, the tumor was characterized by a tubular pattern with alcian- and periodic acid–Schiff–positive secretory material in cystic spaces. The neoplastic cells were positive to broad-spectrum cytokeratins. Histochemical and immunohistochemical stains were consistent with bile duct carcinoma. Biliary tumors arising from the gallbladder have been reported in lions. However, to the authors' knowledge, this is the first case of intrahepatic bile duct carcinoma reported in an African lion.

American Association of Zoo Veterinarians
Elvio Lepri, Monica Sforna, Brachelente Chiara, and Vitellozzi Giovanni "CHOLANGIOCARCINOMA OF INTRAHEPATIC BILE DUCTS WITH DISSEMINATED METASTASES IN AN AFRICAN LION (PANTHERA LEO)," Journal of Zoo and Wildlife Medicine 44(2), 509-512, (1 June 2013). https://doi.org/10.1638/2012-0221R1.1
Received: 20 September 2012; Published: 1 June 2013
JOURNAL ARTICLE
4 PAGES


SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top