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31 December 2013 COMPARISON OF ORAL AND INTRAMUSCULAR RECOMBINANT CANINE DISTEMPER VACCINATION IN AFRICAN WILD DOGS (LYCAON PICTUS)
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Abstract

A series of three doses of recombinant canary-pox–vectored canine distemper virus vaccine was administered at 1-mo intervals, orally (n = 8) or intramuscularly (n = 13), to 21 previously unvaccinated juvenile African wild dogs (Lycaon pictus) at the Wildlife Conservation Society's Bronx Zoo. Titers were measured by serum neutralization at each vaccination and at intervals over a period of 3.5–21.5 mo after the initial vaccination. All postvaccination titers were negative for orally vaccinated animals at all sampling time points. Of the animals that received intramuscular vaccinations, 100% had presumed protective titers by the end of the course of vaccination, but only 50% of those sampled at 6.5 mo postvaccination had positive titers. None of the three animals sampled at 21.5 mo postvaccination had positive titers.

American Association of Zoo Veterinarians
Maren Connolly, Patrick Thomas, Rosie Woodroffe, and Bonnie L. Raphael "COMPARISON OF ORAL AND INTRAMUSCULAR RECOMBINANT CANINE DISTEMPER VACCINATION IN AFRICAN WILD DOGS (LYCAON PICTUS)," Journal of Zoo and Wildlife Medicine 44(4), 882-888, (31 December 2013). https://doi.org/10.1638/2012-0232R2.1
Received: 29 September 2012; Published: 31 December 2013
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