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31 December 2013 ASSESSEMENT OF SERUM AMYLOID A LEVELS IN THE REHABILITATION SETTING IN THE FLORIDA MANATEE (TRICHECHUS MANATUS LATIROSTRIS)
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Abstract

The acute phase protein serum amyloid A (SAA) has been previously shown to have value as a biomarker of inflammation and infection in many species, including manatees (Trichechus manatus latirostris). In the current study, results from an automated assay for SAA were used in a rehabilitation setting. Reference intervals were established from clinically normal manatees using the robust method: 0–46 mg/L. More than 30-fold higher mean SAA levels were observed in manatees suffering from cold stress and boat-related trauma. Poor correlations were observed between SAA and total white blood count, percentage of neutrophils, albumin, and albumin/globulin ratio. A moderate correlation was observed between SAA and the presence of nucleated red blood cells. The sensitivity of SAA testing was 93% and the specificity was 98%, representing the highest combined values of all the analytes. The results indicate that the automated method for SAA quantitation can provide important clinical data for manatees in a rehabilitation setting.

American Association of Zoo Veterinarians
Carolyn Cray, Maya Rodriguez, Meranda Dickey, Leah Brinson Brewer, and Kristopher L. Arheart "ASSESSEMENT OF SERUM AMYLOID A LEVELS IN THE REHABILITATION SETTING IN THE FLORIDA MANATEE (TRICHECHUS MANATUS LATIROSTRIS)," Journal of Zoo and Wildlife Medicine 44(4), 911-917, (31 December 2013). https://doi.org/10.1638/2012-0270R.1
Received: 15 November 2012; Published: 31 December 2013
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