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1 March 2014 ACUTE LYMPHOCYTIC CHOLANGITIS AND LIVER FAILURE IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA)
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Abstract

An adult male Amur tiger (Panthera tigris altaica) with confirmed inflammatory bowel disease developed acute severe icterus, bilirubinuria, bilirubinemia, and elevated bile acids after a diet change. Liver biopsies showed moderate lymphoplasmacytic cholangiohepatitis (lymphocytic cholangitis). The tiger developed neurologic signs including ataxia, tremors, and seizures, as well as epistaxis. Therapy consisted of antibiotics, a steroid anti-inflammatory, vitamins, pro-coagulants, and liver-supportive medicines. The tiger improved from acute liver failure within 3 wk, while the epistaxis began at 3.5 wk and did not resolve until 10.5 wk. The long-term maintenance plan consists of oral prednisolone, metronidazole, ursodiol, and an all muscle-meat beef diet.

American Association of Zoo Veterinarians
Erika K. (Travis) Crook and Nancy A. Carpenter "ACUTE LYMPHOCYTIC CHOLANGITIS AND LIVER FAILURE IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA)," Journal of Zoo and Wildlife Medicine 45(1), 143-147, (1 March 2014). https://doi.org/10.1638/2012-0016R2.1
Received: 16 January 2012; Published: 1 March 2014
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