Translator Disclaimer
1 March 2018 HISTOPATHOLOGIC CHARACTERISTICS OF THYROID GLAND NEOPLASMS IN THOMSON'S GAZELLES (EUDORCUS THOMSONII)
Author Affiliations +
Abstract

Published reports of neoplasms in Thomson's gazelles (Eudorcas thomsonii) are very rare, but thyroid tumors were the most common neoplasm of this species, accounting for 12% of reported pathologies in a 1998–2012 retrospective study of cases submitted for histologic review of grossly enlarged thyroid glands. This report describes the histological and immunohistochemical characteristics of thyroid neoplasms in 10 Thomson's gazelles from five different zoological collections. Neoplasms were submitted as biopsies from six gazelles or collected during necropsy from four gazelles. The most common clinical findings included a palpable mass on the ventral neck and progressive weight loss. Radiographic mineral density was detected in one of the neoplastic masses. Histologically, the neoplasms were classified as microfollicular thyroid adenoma (n = 2), solid thyroid adenoma (n = 2), papillary thyroid adenoma (n = 1), and solid thyroid carcinoma (n = 5). Neoplastic cells in all 10 neoplasms were positive for thyroid transcription factor 1 and thyroglobulin, but negative for calcitonin. While five cases had histologic features of malignancy, there was no evidence of metastatic disease either clinically (biopsies) or on necropsy. Numerous concurrent diseases, including cardiomyopathies and nephropathies, were present and led to choice for euthanasia in several cases.

Copyright 2018 by American Association of Zoo Veterinarians
Stephanie J. French, Michael M. Garner, and Matti Kiupel "HISTOPATHOLOGIC CHARACTERISTICS OF THYROID GLAND NEOPLASMS IN THOMSON'S GAZELLES (EUDORCUS THOMSONII)," Journal of Zoo and Wildlife Medicine 49(1), 64-69, (1 March 2018). https://doi.org/10.1638/2017-0017R1.1
Accepted: 1 November 2017; Published: 1 March 2018
JOURNAL ARTICLE
6 PAGES


SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top