Translator Disclaimer
1 March 2018 MELANOMA IN GOLDEN AND KING WILDEBEESTS (CONNOCHAETES TAURINUS)
Author Affiliations +
Abstract

Pigmentation of the skin is a crucial component in the pathogenesis of melanocytic neoplasms and other skin-related tumors, as melanin is known to function in both the absorbance of ultraviolet radiation and as an antioxidant. Very limited information exists regarding the incidence and metastatic potential of neoplastic conditions of the skin in game animals, especially wildebeests, relative to domestic animals. Four cases of cutaneous melanoma in color-variant golden and king wildebeests (Connochaetes taurinus) (from 2014 to 2015) in South Africa were investigated. Melanoma in these captive animals was characterized using histopathology, transmission electron microscopy, and an immunohistochemistry panel, which consisted of monoclonal antibodies against three melanocytic markers: Melan A, PNL2, and S100. Overall, 2/4 cases (50%) of the melanocytic neoplasms stained strongly positive for all the melanocytic markers, while 4/4 cases (100%) stained positively for at least one of the markers. Cutaneous melanocytic neoplasia has not been reported in wildebeests; the current study suggests that selection of wildebeests for coat color potentially predisposes to this condition.

Copyright 2018 by American Association of Zoo Veterinarians
Shakirat A. Adetunji, Rosina C. Krecek, Nicolize O'Dell, Leon Prozesky, Johan Steyl, and Angela M. Arenas-Gamboa "MELANOMA IN GOLDEN AND KING WILDEBEESTS (CONNOCHAETES TAURINUS)," Journal of Zoo and Wildlife Medicine 49(1), 134-142, (1 March 2018). https://doi.org/10.1638/2017-0059R1.1
Accepted: 1 October 2017; Published: 1 March 2018
JOURNAL ARTICLE
9 PAGES


SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top