Persistence, wash-resistance, and shelf life of mosquito nets treated with a water-dispersible tablet formulation of synthetic pyrethroid insecticide deltamethrin (K-O TAB®) at 25 mg/m2 was evaluated against malaria vectors in India. During June 2001, treated and untreated polyester, nylon, and cotton nets were separately distributed in 3 villages and cone bioassays were performed on Anopheles culicifacies and An. stephensi 1 day after treatment and thereafter every month for 12 months. The mosquitoes were exposed for 3 min on the nettings (treated and unwashed, or treated and washed once or twice in 3 months, and untreated) and knock-down (1 h) and 24 h postexposure mortality were recorded. Unwashed polyester nets, and those washed once 1 month after treatment, gave 100% mortality in An. culicifacies for 6 months. A 2nd wash at 3 months after treatment marginally reduced the insecticidal action. Anopheles stephensi was fully susceptible up to 4 months when exposed to unwashed nets but washing considerably reduced insecticidal action (65–78% after 2 washes). Treated nylon and cotton nets were effective for 4 months on both vectors. Treated nets kept on shelf retained 100% efficacy for 10 months. Overall, the treated nets gave a considerably long persistence of insecticidal action even after a single wash. Treated polyester nets were found most effective. Compared with our earlier experiences of using liquid formulations, the tablet formulation is likely to have a better community acceptance in treating nets.
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Vol. 21 • No. 1