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1 March 2006 INHIBITION OF ADULT EMERGENCE OF AEDES AEGYPTI IN SIMULATED DOMESTIC WATER-STORAGE CONTAINERS BY USING A CONTROLLED-RELEASE FORMULATION OF PYRIPROXYFEN
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Abstract

Concrete domestic water-storage jars are a common larval habitat of the dengue vector Aedes aegypti in countries of Southeast Asia. The efficacy of a novel controlled-release formulation of the insect growth regulator pyriproxyfen, designed to inhibit adult emergence for 6 months (the approximate duration of the main dengue transmission season in many endemic countries) was tested in Cambodia against a local strain of Ae. aegypti in 200-liter jars. The resin-based formulation contained 4.8% active ingredient (AI). At target dosages of 18, 27, and 36 ppb of AI, inhibition of adult emergence remained above 95% for at least 2 months. After 3 months at 18 ppb AI, the residual efficacy was significantly lower than for the higher dosages (P < 0.05). At the higher dosages, inhibition of adult emergence was ≥87% for 6 months. At a dosage of 27 ppb AI, monthly removal and replacement of two thirds of the water did not reduce efficacy (P > 0.05). Potential operational advantages and challenges of using the formulation are discussed. Larger-scale efficacy studies are recommended in community settings.

CHANG MOH SENG, TO SETHA, NGAN CHANTA, DUONG SOCHEAT, PIERRE GUILLET, and MICHAEL B. NATHAN "INHIBITION OF ADULT EMERGENCE OF AEDES AEGYPTI IN SIMULATED DOMESTIC WATER-STORAGE CONTAINERS BY USING A CONTROLLED-RELEASE FORMULATION OF PYRIPROXYFEN," Journal of the American Mosquito Control Association 22(1), 152-154, (1 March 2006). https://doi.org/10.2987/8756-971X(2006)22[152:IOAEOA]2.0.CO;2
Published: 1 March 2006
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