Some studies have reported the low genetic differentiation of Melanaphis sacchari/sorghi and its great phenotypic plasticity to quickly undergo adaptive changes that include change of host and rapid dispersion. In this experiment, damage and behavior of six commercial Sorghum bicolor (L.) Moench hybrids, against attack by the aphid were evaluated at Xalostoc, Morelos. The incidence of the sugarcane aphid from 21 after days sowing (ADS) was observed in all genotypes, despite insecticides coating the seed. The intensity of attack was light (25%) to 35 ADS. The intensity increased at the 49 ADS to (grade 2), with least severity in the Ambar hybrid (50.6%) and the greatest for Milenia (65%). The aphid was most abundant at 56 ADS, with P20 (85%) and Milena (83.7%) the most affected hybrids. At the end of the crop cycle, two groups were formed, the least infested (85 P15, Ambar, and DKS-46) and the most damaged one (Milenia, Cobalt, and 85 P20). Agronomic variables such as fresh weight of the plant, plant height, tang weight, and dry weight of the plant were not different. There were differences only in the brix degrees, with low values for Ambar (3.5°Bx) and P15 (4.2°Bx) hybrids, significantly different from 85 P20 (6.9) and Milena (6.5°Bx).