Translator Disclaimer
1 October 2013 Illuminating the Black Box of Genome Sequence Assembly: a Free Online Tool to Introduce Students to Bioinformatics
Author Affiliations +
Abstract

Next-generation sequencing technologies have greatly reduced the cost of sequencing genomes. With the current sequencing technology, a genome is broken into fragments and sequenced, producing millions of “reads.” A computer algorithm pieces these reads together in the genome assembly process. PHAST is a set of online modules ( http://gcat.davidson.edu/phast) designed to teach advanced high school and college students the genome assembly process. PHAST allows users to assemble phage genomes in real time and includes tutorials detailing the complexities of genome assembly. With PHAST, students learn concepts behind genome assembly and understand how mathematics solves biological problems such as genome assembly.

©2013 by National Association of Biology Teachers. All rights reserved. Request permission to photocopy or reproduce article content at the University of California Press's Rights and Permissions Web site at www.ucpressjournals.com/reprintinfo.asp.
D. Leland Taylor, A. Malcolm Campbell, and Laurie J . Heyer "Illuminating the Black Box of Genome Sequence Assembly: a Free Online Tool to Introduce Students to Bioinformatics," The American Biology Teacher 75(8), 572-577, (1 October 2013). https://doi.org/10.1525/abt.2013.75.8.9
Published: 1 October 2013
JOURNAL ARTICLE
6 PAGES

This article is only available to subscribers.
It is not available for individual sale.
+ SAVE TO MY LIBRARY

SHARE
ARTICLE IMPACT
RIGHTS & PERMISSIONS
Get copyright permission
Back to Top