Traditional transcription-translation exercises are instructionally incomplete by failing to link prescriptive genetic information with protein structure and function. The T3 Method solves this problem by adding a conceptually powerful yet easily learned third step where students use simple protein folding codes to transform their translations into corresponding protein structural models. This brings structural sense to sequence and makes the information-to-proteins connection that is so profoundly important to understand in biology more directly evident, experiential, and intrinsically meaningful. The T3 Method has further utility, proving versatile and adaptive to a wide range of academic levels and learning contexts, with possibilities for differentiated instruction, application, and extension.
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1 April 2017
The T3 Method (“T3 It!”): Transcribe → Translate → Transform
Brett Malas
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The American Biology Teacher
Vol. 79 • No. 4
April 2017
Vol. 79 • No. 4
April 2017
Central Dogma
Genetics
mutation
protein folding
protein structure and function
protein synthesis
transcription