Yellow-throated (Vireo flavifrons) and Red-eyed vireos (V. olivaceus) were observed feeding on green anoles (Anolis carolinensis carolinensis) at two localities in Florida and one in South Carolina. Vireos are long-distance migrants that require foods high in fatty acid content, especially when engaging in migration. It is not unlikely that vireos have an opportunistic foraging strategy to obtain the necessary food requirements, including attacking and consuming prey items such as small lizards. This note provides the first published reports of lizards taken as prey by these two species.