A population of Baptisia alba (Fabaceae) (white wild indigo) in Oktibbeha County, Mississippi was found with a heavy infestation of brentid weevils identified as Trichapion rostrum (Say) (Apioninae). The weevils were observed in high numbers ovipositing on the plants on the side of the road. Forty-nine seed pods were collected and held for maturation of the weevils. After two months, the seed pods were opened and 94 larvae, 61 pupae, and 138 adults were collected. 100% of the pods were infested, and a majority of the seeds in the pods showed heavy feeding damage and were unlikely to germinate. This is also the first time Trichapion rostrum has been reported from Mississippi.