Grizzly bear (Ursus arctos) populations spanning the U.S.–Canada border in the south Selkirk, Purcell–Yaak, and Cabinet Mountains are small, vulnerable, and at the front lines of any further range contraction in North America. Recent genetics work demonstrated that the south Selkirk grizzlies are an isolated population (no male or female connectivity) of fewer than 100 individuals with a 15–20% reduction in genetic diversity and that the Purcell–Yaak population is declining and demographically isolated (no female connectivity) with fewer than 50 individuals. The <25 animals living in the Cabinet Mountains population are likely isolated from both the south Selkirk Mountain and the Purcell–Yaak populations. We recognize these populations need enhanced management. To guide the development of a comprehensive management plan, we explored the effects of 3 actions (population augmentation, enhanced population interchange, and reduced mortality through management actions). We simulated 2 populations of 50 and 100 individuals using population viability analysis (PVA) software (VORTEX). We examined these management actions and combinations of them on population growth rate and extinction probabilities. Our simulations suggest that augmentation had the largest demographic effect on population growth rate over the short-term, mortality reductions had the largest effect in the long-term, and establishing population interchange and reducing mortality had the greatest effect on extinction probability. Enhanced cooperative U.S. and Canadian efforts are required to address the issues facing these small grizzly populations and to build connectivity to existing larger populations and areas of vacant habitat. Our findings apply to recovery and conservation efforts for small populations of all species of bears.