The genus Takulumena of subtribe Epidendrinae, segregated from Epidendrum in 2006 by Szlachetko and co-authors with two species, T. vazquezii and T. sophronitoides, is easily distinguishable from Epidendrum by the monopodial type of growth and the basal, continuously growing inflorescences. Three new species of Takulumena from Ecuador and Peru are described, illustrated and their taxonomic affinities are briefly outlined. Two further species are transferred to Takulumena from Epidendrum and the corresponding new combinations are made. An identification key to all seven species of Takulumena is provided.