Stellaria zhuxiensis Q.L. Gan & X.W. Li sp. nova (Caryophyllaceae) is described and illustrated. The plants are covered with stellate hairs on stems, inflorescences, leaves and sepals. The hairs and the lax, cymose inflorescence are similar to those of S. vestita and S. infracta. Stellaria zhuxiensis can be distinguished from S. vestita by its broader leaves and longer pedicels, longer petals and longer capsules. Stellaria infracta is readily distinguished from S. zhuxiensis by having lanceolate or linear-lanceolate leaves while the leaves of S. zhuxiensis are broadly ovate or ovate-cordate.