The phylogenetic placement of the tribe Dissonomini Medvedev, 1968 (Coleoptera: Tenebrionidae) is investigated using sequences from a historical museum specimen of Dissonomus tibialis Reitter, 1904, along with representative sequences and specimens from the subfamilies Blaptinae (tribes Amphidorini, Blaptini, Dendarini, Opatrini, Pedinini, Platynotini), Tenebrioninae (Bolitophagini, Helopini), Pimeliinae (Adesmini, Sepidiini, Tentyriini, Zophosini), Alleculinae (Alleculini), and Lagriinae (Lagriini). Maximum likelihood and Bayesian analyses were performed on a multi-loci dataset (548 loci spanning 178,309 amino acids). The resulting trees render Dissonomini as sister to Blaptini within Blaptinae with high support. This phylogenetic relation is further supported by morphological traits (e.g., lack ancorae, tenebrionoid protrochanters). As a result, Dissonomini is placed within Blaptinae.