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1 October 2003 The Effect of Dietary Lysine Deficiency on the Immune Response to Newcastle Disease Vaccination in Chickens
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Abstract

SUMMARY. The effect of lysine deficiency on chicken immune function was evaluated using broiler chickens fed a diet with lysine at 67% of the control diet (1.24% lysine). The evaluation of humoral immune function was conducted by measuring the antibody production to a live Newcastle disease virus (NDV) vaccination using the hemagglutination inhibition (HI) test and enzyme-linked immunosorbent assay (ELISA). The cellular immune function was evaluated through the use of cutaneous basophil hypersensitivity test. The antibody response to NDV vaccination was reduced in broiler chickens fed a lysine-deficient diet when measured by ELISA but not when measured by HI. The cell-mediated immune response was also reduced by lysine deficiency.

C. Chen, J. E. Sander, and N. M. Dale "The Effect of Dietary Lysine Deficiency on the Immune Response to Newcastle Disease Vaccination in Chickens," Avian Diseases 47(4), 1346-1351, (1 October 2003). https://doi.org/10.1637/7008
Received: 16 December 2002; Published: 1 October 2003
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