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1 March 2011 Compatibility of Turkey Herpesvirus–Infectious Bursal Disease Vector Vaccine with Marek's Disease Rispens Vaccine Injected into Day-Old Pullets
Stephane Lemiere,, Siam Yit Wong,, Anne-Lise Saint-Gerand,, Sylvain Goutebroze,, François-Xavier Le Gros
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Abstract

Mixtures of turkey herpesvirus (HVT) and Rispens poultry vaccines have been used worldwide for over 20 yr, mainly for vaccination of future layers and breeders. With increasing virulence of Marek's disease (MD) virus strains, vaccination strategies are evolving toward the use of vaccines combining HVT and Rispens. A single vaccination either in ovo or at 1 day of age with the HVT infectious bursal disease (IBD) vector vaccine is efficient against IBD. However, with vaccination programs that include a hatchery administration of the HVT IBD vaccine, additional protection against very virulent and very virulent–plus MD viruses is needed, especially for layers and breeders. This study looked at the combination of four commercially available Rispens vaccines with the HVT IBD vector vaccine injected at 1 day of age. MD challenge tests that were superior to 90% in relative score in all the groups vaccinated with both vaccines showed that the mixture of HVT IBD and Rispens vaccines had no effect on clinical protection against MD, and IBD challenge tests showed that the mixture of HVT IBD and Rispens vaccines had no effect on clinical protection against IBD, which was equal to 100% protection in all the groups vaccinated with both vaccines.

American Association of Avian Pathologists
Stephane Lemiere,, Siam Yit Wong,, Anne-Lise Saint-Gerand,, Sylvain Goutebroze,, and François-Xavier Le Gros "Compatibility of Turkey Herpesvirus–Infectious Bursal Disease Vector Vaccine with Marek's Disease Rispens Vaccine Injected into Day-Old Pullets," Avian Diseases 55(1), 113-118, (1 March 2011). https://doi.org/10.1637/9507-081810-ResNote.1
Received: 18 August 2010; Accepted: 1 December 2010; Published: 1 March 2011
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